Mitsutoshi Setou, MD, received his PhD degree in Medicine in 2001 from the University of Tokyo and since 2008 he is Professor and Chairman of the Department of Cell Biology and Anatomy at the Hamamatsu University School of Medicine. His field of research is molecular anatomy and cell biology with emphasis on characterization of longevity at molecular level and age related diseases. His research interests include development and applications of imaging mass spectrometry (IMS) in biology with “omics” technologies. He is co-author of over 140 peer reviewed papers (having more than 3400 cumulated citations), 14 book chapters, 4 granted patents and is the editor of a book on IMS.
Metabolomics imaging mass spectrometry in clinical research
(Dia-ichi Tsuru, Jun 25th, 09:30)
Metabolomics is the science applied to biological systems aiming to find the metabolite profiles produced by cellular processes at different hierarchical levels. An imaging mass microscope, iMScope, was developed in our laboratory in collaboration with Shimadzu, combining an optical microscope and a state-of-the-art imaging mass spectrometer (IMS) using MALDI (matrix-assisted laser desorption/ionization). The system allows high resolution IMS measurements for targeted sample regions and corroboration of results with histological diagnostic and other findings. An overview of recently obtained results for metabolomics IMS applied to clinical research will be presented.
Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine, Japan